Monday, February 02, 2004

Cancer, Syndromes resulting from inherited defects in DNA repair mechanisms

Another group of hereditary cancers comprises those that stem from inherited defects in DNA repair mechanisms. Examples include Bloom syndrome, ataxia-telangiectasia, Fanconi anemia, and xeroderma pigmentosum. These syndromes are characterized by hypersensitivity to agents that damage DNA (e.g., chemicals and radiation). The failure of a cell to repair the defects

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